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I’ll also examine the top five wagers to place this week during the Big Ten.
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Big Ten best bets at DraftKings
Using odds from DraftKings Sportsbook, the top five wagers for games—including Big Ten teams—are listed below.
Nebraska vs. Illinois
Illinois +8 (-110) is the best bet.
Illinois is traveling here to play Dylan Raiola, Nebraska’s real freshman sensation. Raiola has completed 666 yards, five touchdowns, and one interception on 72.5% of his passes thus far this season. He’s only getting 8.3 yards per attempt on average, and Illinois will be a real defensive test for him.
Illinois gives up 151.7 passing yards and 123 running yards a game. They average 225.3 passing yards and 153.3 running yards per game on offense. With 647 yards, six touchdowns, and zero interceptions on 69.2% of his passes, Luke Altmyer is a capable quarterback.
Both teams will be trying to run the ball, therefore I anticipate this to be a boring game. Recall that in Week 2, Illinois defeated Kansas. Kansas was ranked 19th in the nation at the time.
Although we won’t bet on the moneyline, we like Illinois plus the points since they should stay close.
Ohio State vs. Marshall
Ohio State -40 (-110) is the best bet.
Ohio State, who have only faced Western Kentucky and Akron this season, is 40 points ahead of Marshall at home after their bye week.
While Ohio State’s offense averages 322 passing yards (15th) and 221.5 rushing yards (26th) per game, they only give up 37.5 running yards and 100.5 passing yards per game.
With Marshall shut down by Ohio State’s defense, expect a major blowout.
Michigan vs. USC
USC -5.5 is the best bet (-108)
Following Davis Warren’s three interceptions against Arkansas State, the Wolverines will start Alex Orji. They are 5.5-point underdogs versus USC at home.
Despite having very little collegiate football experience, Orji fits the description of a dual-threat player.
This season, USC’s defense has appeared somewhat more formidable. In addition to giving up 205.5 passing yards per game, they faced LSU quarterback Garrett Nussmeier, who scored more than 300 yards in Week 1.
Miller Moss, the quarterback for USC, is someone I really believe in. He has completed around 72% of his passes and has not committed any turnovers in two games, making him a possible top quarterback in the 2025 NFL Draft.
Although it’s difficult to predict Orji’s starting, USC has shown itself to be a valuable asset this season.
On the point spread for The Big House, I’ll take them at -5.5.
Penn State vs. Kent State
Penn State -49 (-112) is the best bet.
After a bye week, Penn State will host Kent State. Kent State is a really bad football team, even if Penn State narrowly lost to Bowling Green in their most recent game.
Last week, they gave up about 750 offensive yards, including 456 running yards, to Tennessee. I anticipate quarterback Drew Allar to air the ball out more here because Penn State averages well over 200 rushing yards each game.
This is a game that will help Penn State regain its confidence.
Boston College vs. Michigan State
Michigan State +6.5 (-105) is the best bet.
Boston College lost by a slim margin of six on the road against Missouri.
This is going to be an interesting matchup as they host Michigan State in Chestnut Hill.
Michigan State gives up 164 passing yards (ranked 39th) and 78.3 rushing yards (ranked 23rd) per game. Considering that Boston College’s offense averages 204.7 running yards (32nd) and 204 passing yards (89th) per game, this is encouraging.
They may have a problem with Michigan State quarterback Aidan Chiles’ high turnover rate this season, but I expect this program’s running backs, Nate Carter and Kay Ron Lynch-Adams, will be expected to do more.
The Michigan State defense will put up enough effort to keep it close, but I believe Boston College will win because we’ll see two strong defenses play.
Boston College should win 24–20.
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